Stallegra 100mg Tablets

Description

The main element in Stallegra is sildenafil citrate. Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor frequently employed to address erectile dysfunction (ED) by augmenting blood circulation to the penis during sexual arousal, hence facilitating the attainment and sustenance of an erection. The active ingredient is identical to that in brand-name drugs such as Viagra. 

Chemical features of Sildenafil Citrate

• The IUPAC name of Stallegra 100mg is 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate. 
• The chemical formula is C22H30N6O4S (sildenafil base). But when combined with citrate, the full molecular formula becomes C28H38N6O11S.
• Molecular Weight: 666.70 g/mol (sildenafil citrate). 
• Sildenafil citrate is a crystalline powder, white to off-white color.  

What are The Uses of Stallegra 100mg Tablets?

• Erectile Dysfunction treatment

Stallegra 100mg, which typically contains sildenafil citrate, is primarily used for the treatment of erectile dysfunction (ED) in men. Sildenafil citrate belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors, which work by increasing blood flow to the penis, thereby helping to achieve and maintain an erection during sexual stimulation. This medication is highly effective in assisting men with ED to sustain an erection sufficient for sexual activity, but it requires sexual stimulation to work. 

• PAH treatment

In addition to its primary use for ED, sildenafil may also be prescribed under a different brand name and dosage to treat pulmonary arterial hypertension, a condition characterized by high blood pressure in the arteries of the lungs. While Stallegra 100mg may sometimes be used off-label for this purpose, such usage should only be undertaken under strict medical supervision to ensure safety and efficacy.

What are The Dosage Guidelines for Stallegra 100mg Tablets?

For Erectile dysfunction

1. The recommended dose for most men is 100mg, taken orally as needed.
2. It should be taken 30–60 minutes before sexual activity but can be effective when taken up to 4 hours before.
3. For men trying sildenafil for the first time, the doctor might start with a lower dose (e.g., 50mg) to assess tolerance and effectiveness.
4. Based on response and tolerability, the dose can be increased to 100mg or reduced to 25mg.
5. Do not exceed 100mg in a single dose or more than one dose in 24 hours.
6. Stallegra can be taken with or without food, but taking it with a heavy or high-fat meal may delay the onset of action.

For benign prostatic hyperplasia

Stallegra 100mg (sildenafil citrate) is not typically prescribed for the treatment of benign prostatic hyperplasia (BPH), as it is primarily indicated for erectile dysfunction (ED) and sometimes for pulmonary arterial hypertension (PAH). However, another medication in the same class, tadalafil (Cialis), is approved for treating both ED and BPH symptoms.

A starting dose of 25–50mg, taken once daily or as needed, may be recommended, depending on the patient’s response and tolerance. The 100 mg dose is less commonly used for this purpose. If taken for ED and BPH concurrently, the tablet is usually administered 30–60 minutes before sexual activity.It is recommended to take 100mg per day and only under strict medical supervision.

How to Take Stallegra 100mg Tablet?

1. Stallegra can be taken on an empty stomach or with food. Avoid high-fat meals, as they can delay the onset of action by slowing absorption.
2. The timing to take Stallegra 100mg is 30–60 minutes before sexual activity. The medication requires time to be absorbed and take effect.
3. It remains effective for up to 4–6 hours, but this may vary depending on the individual.
4. Make sure you swallow one 100mg tablet with a glass of water. 
5. Do not take more than one dose in 24 hours. 
6. For benign prostatic hyperplasia (BPH), The dose is usually 25–50 mg once daily or as prescribed by a healthcare professional.
7. Never exceed 100 mg in 24 hours, even when used for erectile dysfunction or other off-label conditions.

Missed Dosage Guidelines

For Erectile Dysfunction

Missed dosage is not applicable in ED because it has to be taken whenever one want to have sex. If you forget to take Stallegra before planned sexual activity, simply take it when you remember, ensuring there is sufficient time (30–60 minutes) before sexual activity. Do not take more than one dose in a 24-hour period.

For BPH

If Stallegra is being taken daily for BPH symptoms:

1. Take the missed dose as soon as you remember, provided it is not close to the next scheduled dose.
2. If it’s almost time for your next dose, skip the missed dose and resume your regular dosing schedule.
3. Do not double the dose to make up for the missed one.

Overdosage guidelines

1. You need to make sure that you don’t try to self adjust the prescribed dose.
2. You also need to make sure that you don’t combine alcohol or recreational drugs which can amplify the effect. 
3. You have to be cautious about the interaction of this drug with nitrate medications or alpha blockers. 

What to Do in Case of An Overdose? 

Promptly seek medical assistance if you observe symptoms such as the following: 

1. severe migraines
2. Dizziness, 
3. unusually prolonged erection. 

The therapy for an overdose will depend on the severity of the patient’s symptoms and may involve alleviating those symptoms or offering supportive care.

How does Stallegra 100mg Tablet Work?

Stallegra 100mg, assuming it operates analogously to sildenafil (Viagra) or other phosphodiesterase type 5 (PDE5) inhibitors, augments blood flow to the penis, facilitating the attainment and sustenance of an erection during sexual arousal. The following elucidates its method of action:

Sexual Stimulation and Nitric Oxide Release:

• During sexual arousal, nerve endings in the penis release nitric oxide (NO).
• Nitric oxide (NO) activates an enzyme called guanylate cyclase, which increases levels of cyclic guanosine monophosphate (cGMP).

Role of cGMP:

• cGMP causes the smooth muscles in the blood vessel walls of the penis to relax (vasodilation).
• This relaxation allows increased blood flow into the spongy tissues of the penis (corpora cavernosa), leading to an erection.

Inhibition of PDE5:

• Normally, an enzyme called PDE5 breaks down cGMP, which ends the erection.
• Stallegra inhibits PDE5, allowing cGMP levels to remain elevated for longer, sustaining the erection.

It’s extended duration of action Takes about 30 minutes to 1 hour to start working. The Effects last approximately 4–6 hours, although this varies between individuals.

What are The Side Effects of Stallegra 100mg Tablets?

These are usually mild and may resolve as your body adjusts to the medication:

1. Headache
2. Flushing (warmth, redness, or tingling, especially in the face and neck)
3. Nasal Congestion or a runny nose
4. Upset Stomach or indigestion (dyspepsia)
5. Dizziness or lightheadedness
6. Vision Changes:
   • Blurred vision
   • A bluish tint to vision (cyanopsia)
   • Increased sensitivity to light (photophobia)
7. Back Pain or muscle aches (myalgia)

Precautions and Warnings

1. Patients with a medical history of the following should avoid Stalegra 
2. Heart disease,heart failure, or a history of heart attack or stroke
3. Blood pressure issues 
4. Eye disorders
5. Kidney or liver disease
6. Stomach ulcers 
7. Conditions like angina, arrhythmias
8. Sexual activity can strain the heart; this medication may not be safe for individuals with severe heart disease.
9. Avoid combining the drug with any nitrates which can cause in severe drop of blood pressure. 
10. Make sure that you don’ t combine Stallegra with alpha blockers, PDE5 inhibitors, certain antibiotics or antifungals, HIV Protease inhibitors
11. Certain conditions where using Stalllegra 100mg can be riskier are severe hypotension, any recent surgery, pregnancy and breastfeeding.

Things to keep in mind when taking Stallegra 100mg:

1. Make sure that you do not exceed the recommended dose. 
2. Take the medication, 30 minutes of before indulging into sexual activity. 
3. High fat meals may delay the onset of action of the drug. 
4. Consumption of alcohol can decrease =the effect of themedication and even increase  the chances of side effects like dizziness or low blood pressure.
5. Always follow the advice of your healthcare provider and discuss any concerns before starting Stallegra 100mg.

When Not to Take Stallegra 100mg Tablet?

1. Taking medications containing nitrates (e.g., nitroglycerin, isosorbide mononitrate/dinitrate) for heart conditions or angina should avoid taking Stallegra 100mg because the combination can cause a severe drop in blood pressure, leading to fainting, stroke, or even heart attack. 

If you have:

• Unstable angina.
• Severe heart failure.
• A recent history of heart attack (within the past 6 months).
• Severe arrhythmias or uncontrolled irregular heart rhythms.
• A history of stroke (within the past 6 months).

If you have a history of sudden hearing loss or other unexplained auditory problems, avoid use without consulting a doctor. 

Interaction

1. Do not take Stallegra with nitroglycerins, iso-sorbite mononitrate, recreational drugs like butyl nitrates and that is because there shall be a drop in blood pressure which may lead to dizziness, fainting, heart attack or stroke. 
2. Taking more than one ED medication can significantly increase the risk of side effects like priapism (prolonged erection), severe hypotension, and cardiovascular strain. 
3. Drugs that slow down the metabolism of Stallegra and increase its levels in the bloodstream, leading to a higher risk of side effects:
4. Antifungals: Ketoconazole, itraconazole.
5. HIV Protease Inhibitors: Ritonavir, saquinavir.
6. Antibiotics: Erythromycin, clarithromycin.
7. Hepatitis C Medications: Boceprevir, telaprevir.

Recommendation: Dose adjustment may be necessary if you’re taking any of these medications.

FAQs:

Q. Who should avoid taking Stallegra 100mg?

Avoid if taking nitrates, alpha-blockers, or if you have severe heart, liver, or eye conditions.

Q. How should I take Stallegra 100mg?

Take one tablet 30-60 minutes before sex, not exceeding one dose in 24 hours.

Q. Can I take Stallegra with alcohol?

Avoid excessive alcohol, as it may worsen side effects like dizziness and low blood pressure.

Q. What are common side effects?

Headache, flushing, dizziness, nasal congestion, and mild vision changes are common.

Q. Can I take Stallegra 100mg every day?

It’s not recommended for daily use unless explicitly prescribed by a doctor. Only take once in 24 hours or as directed by a healthcare professional.